COMPUTERS NEEDED FOR THE CURE OF DISEASES…YOU CAN HELP!

Today, we launch a new initiative aimed at overcoming one of the toughest problems in finding preventions, treatments and cures for orphan, rare and neglected (ORN) diseases…crossing the chasm from protein target to drug candidate molecule. Traditionally, this step requires screening many potentially active molecules – a time consuming and expensive process. That’s because until now, researchers had few alternatives; either they used less selective computational tools, and settled for longer lists of molecules that held less promise, or they consumed time and resources in high throughput screening, hoping to find a good candidate to take onward into development.

Starting now, researchers and those committed to preventing, treating and curing ORN diseases have a powerful tool – Inverse Design™. Quantum Cures Foundation will provide this computational tool to research organizations free of charge. Collaborators will just have to provide us with a protein target having an X-ray structure, and work with us to design some molecular starting points (we call them “scaffolds”). Then, we will use the power of donated computer time to design new drug and vaccine candidate molecules.

Please…if you, or someone you know is involved in ORN disease research, spread the word.  Quantum Cures wants to help.

Lawrence Husick, Exton, PA, US, 28-FEB-13 (International Rare Disease Day!)

12 Responses to “COMPUTERS NEEDED FOR THE CURE OF DISEASES…YOU CAN HELP!”

  • Brian:

    This is a great thing you are doing!

  • Tarek Hoteit:

    Thanks for the post. I went to sign up, but unfortunately you don’t have Linux as one of the OS platforms under the waiting list form.

    • this is a big downside. I have two datacenters with more than 500 multi-processor/core boxes that sit idle for 12 hours a day..but the run ubuntu and centos.

      • admin:

        Paul, we are working with corporate donors to apply grid and HPC clusters idle cycles to specific projects. Feel free to contact me to discuss how we might be able to work together to capture your idle cycles..

        John McGrath
        jmcgrath@quantumcures.org

    • admin:

      Yes we have Linux as one of the drop down menu options on our sign up page. Thanks for your interest!

  • radlad:

    I cannot wait to help.

  • Jeremy:

    This is great, looking forward to it :)

  • Amy:

    Such an awesome project! I saw that you had Android and iOS listed as operating systems– what if I wanted to donate time on more than one device– for instance– Windows and my Android phone?

  • Dave:

    How is this different that WorldCommunityGrid.org? And, what quantum drug design software are you going to use?

    • admin:

      Worldcommunitygrid.org is focus on providing computer resources for general computing requirements. QuantumCures is focused specifically on applying volunteer computing resourses as well as cloud based computing donations to the application of Inverse Design and other insilco drug dicovery capabilties to research on rare and neglected diseases. Our efforts tend to be project based, focused on specific advancements against targets under investigation. Our benefit is to accelerate the drug discovery process, specifically the indentification of effective molecules that can be developed into treatments.

  • FAZIA:

    Would you consider working on an increasingly common condition like
    Multiple chemical sensitivity/MCS that can be disabling in severity eg Gulf War Syndrome

    • admin:

      Quantum Cures help researchers identify small molecules that can be used as inhibitors for treatement. We would be glad to discuss supporting rsearch of this type, but would need to ualify the targets being studied and whether we could help accelerate specific projects. We would be glad to talk to researchers doing work in this area.

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February 25th, 2013

COMPUTERS NEEDED FOR THE CURE OF DISEASES…YOU CAN HELP!

Today, we launch a new initiative aimed at overcoming one of the toughest problems in finding preventions, treatments and cures for orphaREAD POST >>

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